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Description
GBP1 Recombinant Rat mAb (S-R186)Product Specification Host Rat Antigen GBP1 Synonyms Guanylate binding protein 1; GTP binding protein 1; GBP 1; HuGBP 1; hGBP1; Guanine nucleotide binding protein 1; Interferon induced guanylate binding protein 1 Location Cell membrane, Golgi apparatus membrane, Cytoplasm, Secreted Accession P32455 Clone Number S R186 Antibody Type Rat mAb Isotype IgG1 Application WB, IHC P, ICC, IP Reactivity Hu Purification Protein G Concentration 2 mg ml
Product Specification
| Host | Rat |
| Antigen | GBP1 |
| Synonyms | Guanylate-binding protein 1; GTP-binding protein 1; GBP-1; HuGBP-1; hGBP1; Guanine nucleotide-binding protein 1; Interferon-induced guanylate-binding protein 1 |
| Location | Cell membrane, Golgi apparatus membrane, Cytoplasm, Secreted |
| Accession | P32455 |
| Clone Number | S-R186 |
| Antibody Type | Rat mAb |
| Isotype | IgG1 |
| Application | WB, IHC-P, ICC, IP |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 | |
| IHC | 1:100 | |
| ICC | 1:500 |
Background
A single cluster of seven human GBP genes (GBP1-GBP7) is found on chromosome 1q22.2. Human GBP1 is secreted from cells without the need of a leader peptide, and has been shown to exhibit antiviral activity against Vesicular stomatitis virus and Encephalomyocarditis virus, as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to IFN-gamma [PMID: 16936281].
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