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Description
Mouse Anti-Human CD360 Antibody (S-3285)Product Specification Host Mouse Antigen CD360 Synonyms Interleukin 21 receptor; IL 21 receptor; IL 21R; Novel interleukin receptor; IL21R; NILR Location Membrane Accession Q9HBE5 Clone Number S 3285 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from
Product Specification
| Host | Mouse |
| Antigen | CD360 |
| Synonyms | Interleukin-21 receptor; IL-21 receptor; IL-21R; Novel interleukin receptor; IL21R; NILR |
| Location | Membrane |
| Accession | Q9HBE5 |
| Clone Number | S-3285 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
The CD360 protein, also known as the B-cell receptor CD360 or Leukocyte Immunoglobulin-Like Receptor B1 (LILRB1), is an inhibitory receptor primarily expressed on the surface of immune cells such as B cells, monocytes, dendritic cells, and NK cells. Belonging to the Leukocyte Immunoglobulin-Like Receptor (LILR) family, it recognizes ligands like MHC class I molecules (e.g., HLA-G) and transmits inhibitory signals, thereby negatively regulating immune responses. It plays a critical role in maintaining immune homeostasis, preventing excessive activation, and mediating immune escape. Dysregulation of its function is closely associated with autoimmune diseases, infections, and tumor immune evasion, making it a potential target for immunotherapy research.
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