Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 10 - Sep 15
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Fc gamma RIIIa/CD16a Mouse mAb (S-564-39)Product Specification Host Mouse Antigen Fc gamma RIIIa CD16a Synonyms Low affinity immunoglobulin gamma Fc region receptor III A, IgG Fc receptor III A, CD16 II, CD16a antigen, Fc gamma RIII alpha, Fc gamma RIII, FcRIII, FcRIIIa, FcgammaRIIIA, FcR 10, IgG Fc receptor III 2, FCGR3A, FCG3, FCGR3, IGFR3 Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession P08637 Clone Number S 564 39 Antibody Type Mouse mAb Isotype IgG1,k Application
Product Specification
| Host | Mouse |
| Antigen | Fc gamma RIIIa/CD16a |
| Synonyms | Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, FCGR3A, FCG3, FCGR3, IGFR3 |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane |
| Accession | P08637 |
| Clone Number | S-564-39 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300/ |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | null |
Background
CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in triggering lysis by NK cells, CD16 is a molecule of the immunoglobulin superfamily (IgSF) involved in antibody-dependent cellular cytotoxicity (ADCC). It can be used to isolate populations of specific immune cells through fluorescent-activated cell sorting (FACS) or magnetic-activated cell sorting, using antibodies directed towards CD16. CD16 plays a significant role in early activation of natural killer (NK) cells following vaccination. In addition, CD16 downregulation represents a possible way to moderate NK cell responses and maintain immune homeostasis in both T cell and antibody-dependent signaling pathways.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy