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Description
IL-9 His Tag Protein, HumanProduct Specification Species Human Synonyms Interleukin 9; IL 9; Cytokine P40; T cell growth factor P40; HP40; P40 Accession P15248 Amino Acid Sequence Gln19 Ile144, with His tag at the C Terminus. Expression System HEK293 Molecular Weight The protein has a predicted MW of 15. 3 kDa. Due to glycosylation, the protein migrates to 40 50 kDa based on Bis Tris PAGE result. Purity > 95% as determined by Bis Tris PAGE& HPLC Endotoxin <1EU g Conjugation
Product Specification
| Species | Human |
| Synonyms | Interleukin-9; IL-9; Cytokine P40; T-cell growth factor P40; HP40; P40 |
| Accession | P15248 |
| Amino Acid Sequence | Gln19-Ile144, with His tag at the C-Terminus. |
| Expression System | HEK293 |
| Molecular Weight | The protein has a predicted MW of 15.3 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
| Purity | > 95% as determined by Bis-Tris PAGE& HPLC |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20mM Tris, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases.
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