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Description
Biotin Armenian hamster Anti-Mouse CD196 Antibody (S-R621)Product Specification Host Armenian hamster Antigen CD196 Synonyms C C chemokine receptor type 6; C C CKR 6; CC CKR 6; CCR 6; KY411; Cmkbr6; Ccr6 Location Cell membrane Accession O54689 Clone Number S R621 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin
Product Specification
| Host | Armenian hamster |
| Antigen | CD196 |
| Synonyms | C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; KY411; Cmkbr6; Ccr6 |
| Location | Cell membrane |
| Accession | O54689 |
| Clone Number | S-R621 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD196, also known as CCR6, is a ~42 kDa G protein-coupled seven-transmembrane chemokine receptor expressed on immature dendritic cells, memory T and B cells, NK cells and Langerhans cells; it binds the unique ligand CCL20 (MIP-3α), triggering calcium signaling that directs chemotactic recruitment of these cells to epithelial and inflamed tissues, thereby orchestrating mucosal immunity, Th17 and regulatory T-cell differentiation, B-lineage maturation, and pathogenic inflammatory circuits in diseases such as psoriasis, rheumatoid arthritis and inflammatory bowel disease.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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