SKU: 68011463033

NeuN Recombinant Rabbit mAb (S-392-1)

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Description

NeuN Recombinant Rabbit mAb (S-392-1)Product Specification Host Rabbit Antigen NeuN Synonyms RNA binding protein fox 1 homolog 3, Fox 1 homolog C, Neuronal nuclei antigen (NeuN antigen), RBFOX3 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession A6NFN3 Clone Number S 392 1 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid

Product Specification


Host Rabbit
Antigen NeuN
Synonyms RNA binding protein fox-1 homolog 3, Fox-1 homolog C, Neuronal nuclei antigen (NeuN antigen), RBFOX3
Immunogen Synthetic Peptide
Location Cytoplasm, Nucleus
Accession A6NFN3
Clone Number S-392-1
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P, ICC, ICFCM, IP
Reactivity Hu, Ms, Rt
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution


application dilution species
WB 1:1000
IHC 1:500
ICC 1:500
IP 1:50

Background

NeuN (Fox-3, Rbfox3, or Hexaribonucleotide Binding Protein-3), a protein which is a homologue to the protein product of a sex-determining gene in Caenorhabditis elegans, is a neuronal nuclear antigen that is commonly used as a biomarker for neurons. NeuN antibodies are widely used to label neurons. A few neuronal cell types are not recognized by NeuN antibodies, such as Purkinje cells, stellate and Golgi cells of the cerebellum, olfactory Mitral cells, retinal photoreceptors and spinal cord gamma motor neurons. However the vast majority of neurons are strongly NeuN positive, and NeuN immunoreactivity has been widely used to identify neurons in tissue culture and in sections and to measure the neuron/glia ratio in brain regions. NeuN immunoreactivity becomes obvious as neurons mature, typically after they have downregulated expression of Doublecortin, a marker seen in the earliest stages of neuronal development.

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SKU: 68011463033

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