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Description
FGF-basic(154aa) Protein, HumanProduct Specification Species Human Synonyms bFGF,FGF 2Heparin binding growth factor 2Basic fibroblast growth factorFGFB,HBGF 2FGF2Fibroblast Growth Factor 2 (Basic) Accession P09038 Amino Acid Sequence Ala135 Ser288 Expression System E. coli Molecular Weight 17 18kDa(Reducing) Purity 95%, by SDS PAGE under reducing conditions Endotoxin <1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM PB, 500mM
Product Specification
| Species | Human |
| Synonyms | bFGF,FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB,HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic) |
| Accession | P09038 |
| Amino Acid Sequence | Ala135-Ser288 |
| Expression System | E.coli |
| Molecular Weight | 17-18kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 500mM NaCl, pH7.4 |
| Reconstitution | Reconstitute at 0.5 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
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