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Description
Rat Anti-Mouse IL-2 Antibody (S-R536)Product Specification Host Rat Antigen IL 2 Synonyms Interleukin 2; T cell growth factor (TCGF); Il 2; Il2 Location Secreted Accession P04351 Clone Number S R536 Antibody Type Rat mAb Isotype IgG2b,k Application ICFCM Reactivity Ms Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Dilution
Product Specification
| Host | Rat |
| Antigen | IL-2 |
| Synonyms | Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2 |
| Location | Secreted |
| Accession | P04351 |
| Clone Number | S-R536 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | ICFCM |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICFCM | 1:200 | Ms |
Background
Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.
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