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Description
Galectin-4 His Tag Protein, HumanProduct Specification Species Human Synonyms Galectin 4, LGALS4, L36LBP, Antigen NY CO 27, Lactose binding lectin 4 Accession P56470 1 Amino Acid Sequence Met 1 Ile323, with N 8*His Expression System HEK293 Molecular Weight 38 42kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4, 2mM DTT Reconstitution Reconstitute at 0. 1 1 mg ml according to the size
Product Specification
| Species | Human |
| Synonyms | Galectin-4, LGALS4, L36LBP, Antigen NY-CO-27, Lactose-binding lectin 4 |
| Accession | P56470-1 |
| Amino Acid Sequence | Met 1-Ile323, with N-8*His |
| Expression System | HEK293 |
| Molecular Weight | 38-42kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 2mM DTT |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Yang R Y. et al. 2008 Galectins: structure, function and therapeutic potential. Expert Rev Mol Med. 10: e17. 2、Ideo H. et al. 2007 Recognition mechanism of galectin-4 for cholesterol 3-sulfate. J Biol Chem. 282(29): 21081-21089. |
Background
Galectins are a family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins.Galectin-4, a tandem-repeat-type lectin with affinity to sulfatide and nonsialylated termini of N-glycans, has the ability to regulate adhesion of cells to ECM components and is also involved in polarized membrane trafficking.Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. Galectin-4 can also bind lung, spleen and kidney macrophages, although its expression is normally low in these tissues. Neurons and OLGs were identified as a possible source of galectin-4, both in vitro and in vivo. In culture, neurons but not OLGs released galectin-4. In co-cultures, a reduced release of endogenous galectin-4 correlated with the onset of myelination. Galectin-4-reactive sites are transiently expressed on processes of premyelinating primary OLGs, but not on neurons. Neuronal galactin-4 is a candidate for a soluble regulator of OLG differentiation and myelination.
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4.5 ★★★★★
Based on 11 reviews
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Product Reviews
★★★★★ 5
Can't go wrong with Acorn for as long as they last!
Size: 12-13 Women/10.5-11.5 Men, Color: Charcoal
Acorn is just a great company all around. I had bought my husband these slippers over 20 years ago. They are still in great shape although the sole has worn in some places. But nothing's coming apart! However, I decided to replace them for him. His foot is 10.5 and they are a little hard to get on right away-of course, after over 20 years of having "worn in" the original pair, anything would feel tight. So I'm not holding this against them. They will relax with use. The only difference is that the original sole was black and these are tan. I think I would prefer the black, but since it's only being worn in the house, no big deal.
My husband has really cold feet and these slippers never fail to warm his feet right up! He said they feel really soft to walk in and like the cushioning. They're not too heavy and fit him great! I have Acorn slippers myself that I've worn every single day in the house and outside to the mailbox too. They last.
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Reviewed in the United States on April 11, 2026
★★★★★ 4
Very warm.
Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue
Very warm and comfortable. A little difficult to put on with the collared top.
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Reviewed in the United States on January 19, 2026
★★★★★ 5
You won't be sorry
Size: 10.5-11.5 Women/9-10 Men, Color: Black
Great padding for comfort and terrific warmth. I bought a pair of Acorns 30 years ago and still have them. Updated to a new color and now feel the benefit of newer padding! I used the sizing listed for shoes and like the roominess for thicker sox. Well made and a joy to put on. (Wisconsin)
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Reviewed in the United States on December 25, 2025
★★★★★ 5
Great Slippers
Size: 12-13 Women/10.5-11.5 Men, Color: Charcoal
Comfy, great price, looks great, fits well, size aligned, great quality. Love these slippers.
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Reviewed in the United States on February 16, 2026
★★★★★ 5
Extremely comfortable, leather sole. Hard to find a style.
Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue, Size: 13.5-14.5 Women/12-13 Men, Color: Navy Blue
Totally worth the price. This type of style is very hard to find, my husband had another pair a few years ago that he was never able to replace. These fit his wide feet and are very comfortable. The elastic at the ankle is not too tight. So glad I was able to find him a replacement. We bought the blue in a size 12. Love the fact that they are washable.
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Reviewed in the United States on February 12, 2026
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