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Description
Ctip2 Recombinant Rabbit mAb (S-R314)Product Specification Host Rabbit Antigen Ctip2 Synonyms BCL11B, Ctip2, RIT1 Location Nucleus Accession Q9C0K0 Clone Number S R314 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as supplied
Product Specification
| Host | Rabbit |
| Antigen | Ctip2 |
| Synonyms | BCL11B, Ctip2, RIT1 |
| Location | Nucleus |
| Accession | Q9C0K0 |
| Clone Number | S-R314 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
Background
CTIP2 (also known as BCL11B) is a transcription factor Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. CTIP2 deficiency results in structural striatal defects, impaired spatial learning, and working memory deficits in mice. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Diseases associated with CTIP2 include Immunodeficiency and Intellectual Developmental Disorder with Speech Delay, Dysmorphic Facies, And T-Cell Abnormalities. Among its related pathways are NF-kappaB Signaling and Development and heterogeneity of the ILC family.
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