SKU: 59863304929

Mouse Anti-Human TCR α/β Antibody (S-R686)

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Description

Mouse Anti-Human TCR α/β Antibody (S-R686)Product Specification Host Mouse Antigen TCR Synonyms TCR; TCR Location Cell membrane Accession P01848 P01850 Clone Number S R686 Antibody Type Mouse mAb Application FCM Reactivity Hu Positive Sample Human PBMC Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied. Dilution application dilution species FCM 1: 200 Hu

Product Specification


Host Mouse
Antigen TCR α/β
Synonyms α/β TCR; TCR α/β
Location Cell membrane
Accession P01848、 P01850
Clone Number S-R686
Antibody Type Mouse mAb
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:200 Hu

Background

The T cell receptor (TCR) α and β proteins are essential components of the αβ T cell receptor, a heterodimeric surface protein expressed on T lymphocytes that recognizes antigenic peptides presented by major histocompatibility complex (MHC) molecules. The TCR α chain is encoded by the TRAC (T cell receptor alpha constant) and TRAV (T cell receptor alpha variable) genes, while the TCR β chain is encoded by the TRBC (T cell receptor beta constant) and TRBV (T cell receptor beta variable) genes, along with diversity (TRBD) and joining (TRBJ) segments, enabling extensive combinatorial diversity. Structurally, both chains consist of a variable (V) domain responsible for antigen recognition and a constant (C) domain that anchors the receptor to the cell membrane. The TCR αβ heterodimer associates with the CD3 complex (CD3γε, CD3δε, and CD247 ζζ) to form a functional TCR-CD3 signaling unit, which transmits activation signals upon peptide-MHC engagement. TCR β undergoes V(D)J recombination during thymic development, contributing to the receptor's antigen specificity, whereas TCR α lacks a D segment but still undergoes recombination for diversity. Mutations or dysregulation in TCR α/β genes can lead to immune disorders, including T cell malignancies and autoimmune diseases. TCR αβ T cells are critical for adaptive immunity, mediating responses against infections, tumors, and self-antigens in autoimmune conditions.

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SKU: 59863304929

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4.9 ★★★★★
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C
Cheryl Belle
Carnegie, US
★★★★★ 3
Thin, summer weight throw, quality could be better
Color: Southern Blues, Size: Throw (50 in x 60 in), Color: Southern Blues, Size: Throw (50 in x 60 in)
This is a very light weight blanket and the "fleece" is no where to be seen. The blanket looks like cotton but has a very synthetic feel to it. Three layers implies some weight but it is thin. The construction is sloppy, see images, where the stitching looks slap dash to the point where it cannot be reversed. I liked the color, the blue is a little on the aqua side but it is a very nice calming hue. The stitching is quilt like and nicely done. I noticed other reviews felt like it was a medium weight but the only time I would use this would be to use as a cover if the AC went out. To me, the blanket is decorative and not particularly useful.
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Reviewed in the United States on May 15, 2026
H
Hayden
Waukegan, US
★★★★★ 4
Average quality lightweight throw, not sold on the color
Color: Southern Blues, Size: Throw (50 in x 60 in), Color: Southern Blues, Size: Throw (50 in x 60 in)
This blanket is fairly soft and lightweight, and better suited for the summer months. I don't think the texture and "Southern Blues" color looks as nice in person as in the photos; less cozy and more like a spare blanket you might find in a hotel closet. Interestingly the care tag says that the outer faces are cotton, but the blanket feels polyester and the content tag indicates the same. The stitching and durability feel ok, and it will probably hold up for the occasional machine washing and low heat drying. Overall it's a fine warm season throw but not particularly notable. I would probably recommend one of the darker colors.
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Reviewed in the United States on May 23, 2026
C
circusdaze
Boise, US
★★★★★ 5
So easy to wash!
Color: Southern Blues, Size: Full/Queen (90 in x 90 in), Color: Southern Blues, Size: Full/Queen (90 in x 90 in)
Two things I love about this coverlet: 1. It's so much easier to wash than a duvet! Or even a duvet cover or a regular blanket, for that matter. The queen-size coverlet fit easily in my washer, and I could have put in another if I had had one. It stayed loose and balanced in the machine - the washer didn't have to readjust its balance during the spin cycles. In the dryer, it didn't wad up into a ball that had to be shaken out every few minutes. It came out feeling softer and looking good, with no wrinkles. 2. It's thinner than a duvet and suitable for warm weather, yet those three stitched layers give it substance and weight that I find more comfortable than sleeping under a pile of fluff or a bed sheet. The soft pastel green color with cream lining (not really reversible due to the hem) is fresh and reminiscent of the 1950s coverlets that my grandmother made. Crocheting was one of her passions, and she'd create huge lacy doilies that lay across the foot of the coverlet. Very pretty look.
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Reviewed in the United States on May 1, 2026
C
Chimi
Phoenix, US
★★★★★ 5
Great summer blanket.
Color: Black, Size: Full/Queen (90 in x 90 in)
I purchased this Berkshire 3-layer fleece blanket, and it has quickly become my go-to for my queen size bed. It fits perfectly with plenty of overhang, making it look great as a top layer or a middle layer.What I love most is the breathability. While the material is technically fleece, the 3-layer design provides a nice "cotton-like" feel that doesn't feel heavy or stifling. I tend to sleep hot, and this blanket does a fantastic job of keeping me cool and comfortable through the night while still providing just enough cozy warmth.At this price point, the value is good. It feels much higher quality than other thermal blankets I’ve tried, and it holds up well in the wash without pilling or losing its softness. If you're looking for a versatile, lightweight blanket that works year-round, this is a solid choice. Highly recommended!
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Reviewed in the United States on May 9, 2026
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aposhsavage
Phoenix, US
★★★★★ 5
Fab , chic, furry & perfect for HTX weather
Five stars because I’m super picky about my main blanket and after two years I finally found one that will be as good as the one with 70 holes that I’ve been holding onto like a 7 year old. It’s super furry, and soft and the solid black side is smooth. Its not too heavy , its the best kind of thin which is perfect for Houston Texas. It’s just how I like my go to blanket. I have tons of blankets but there’s always one that’s my most favorited and now, this one will be for the next however many years. It’s a FAB design too. Love!
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Reviewed in the United States on May 7, 2026

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