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Description
S-RMab® FOXP3 Recombinant Mouse mAb,PBS Only (SDT-R149)Product Specification Host Mouse Antigen FOXP3 Synonyms Forkhead box prote 1, Forkhead box protein P3, Scurfin Immunogen N A Location Nucleus Accession Q9BZS1 Clone Number SDT R149 Antibody Type Recombinant mAb Isotype IgG1 Application WB, IHC P Reactivity Hu Purification Protein G Concentration 2 mg ml Tag N A Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt, 4C as supplied Dilution application dilution
Product Specification
| Host | Mouse |
| Antigen | FOXP3 |
| Synonyms | Forkhead box prote 1, Forkhead box protein P3, Scurfin |
| Immunogen | N/A |
| Location | Nucleus |
| Accession | Q9BZS1 |
| Clone Number | SDT-R149 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1 |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Tag | N/A |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt, 4°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 |
Background
FOXP3 is a transcription factor, which belongs to the family of FOX protein. FOXP3 was initially discovered in regulatory T cells and supposed to play a significant role in the process of regulatory T cell differentiation. Increasing evidence has shown that FOXP3 is also expressed in tumor cells. In some types of human cancers, the expression of FOXP3 is upregulated, and it can promote the development of cancers, leading to a poor prognosis [PMID: 30630091].
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Exchange/Return Notes
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