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Description
S-RMab®Steroidogenic Factor 1/SF-1 Recombinant Rabbit mAb,PBS Only (SDT-1666-11)Product Specification Host Rabbit Antigen Steroidogenic Factor 1 SF 1 Synonyms STF 1; hSF 1; Adrenal 4 binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP; NR5A1; AD4BP, FTZF1, SF1 Immunogen Synthetic Peptide Location Nucleus Accession Q13285 Clone Number SDT 1666 11 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Positive Sample human adrenal gland,
Product Specification
| Host | Rabbit |
| Antigen | Steroidogenic Factor 1/SF-1 |
| Synonyms | STF-1; hSF-1; Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP; NR5A1; AD4BP, FTZF1, SF1 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q13285 |
| Clone Number | SDT-1666-11 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Hu |
| Positive Sample | human adrenal gland, human testis |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:100 | Hu |
Background
SF-1 (Steroidogenic Factor 1) is a 52-kDa nuclear receptor transcription factor that activates the promoters of many key genes involved in steroidogenesis, adrenal development, and reproduction (CYP11A, CYP11B, CYP21B, AHCH, STAR, etc.) within the body. It is expressed in the adrenal gland and reproductive axis both during fetal development and in adulthood. High expression is observed in the adrenal cortex, pituitary, ovaries (granulosa and theca cells), testes (sertoli and leydig cells), and spleen.
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Exchange/Return Notes
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