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Description
Human IgG4 Fc , His tagProduct Specification Species Human Synonyms Ig gamma 4 chain C region, IGHG4 Accession P01861 Amino Acid Sequence Protein sequence(P01861, Glu99 Gly326, with C 10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight
Product Specification
| Species | Human |
| Synonyms | Ig gamma-4 chain C region, IGHG4 |
| Accession | P01861 |
| Amino Acid Sequence | Protein sequence(P01861, Glu99-Gly326, with C-10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.3kDa Actual:33kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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4.8 ★★★★★
Based on 12 reviews
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Product Reviews
★★★★★ 1
I always ignore the buyer beware post but this is a buyer beware post!
I purchased this product based on the reviews I read. Please do not purchase. The cartridge is totally different from the brand version
The part of the cartridge that should be fastened and locked into the pen is shaped in a circle , on the pen the Parr is rectangle . The original cartridge has a circular downward pattern to help lock the cartridge into the machine on the replacement cartridge there's no ridges it just slides down so it doesn't fit in no way shape form or fashion. I tried to alter the circular piece to make it fit by filing, burning and reshaping the plastic in an attempt to change the shape to a rectangle to fit it doesn't work the entire cartridge does not fit into the machine it's a waste of money for product that can't be returned or used. Buyer beware!
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Reviewed in the United States on January 22, 2025
★★★★★ 5
Great insights and easy to understand
Format: Paperback
I love the Passion Translation. I look forward to Exodus and some of the other books being translated in the Old Testament. Right now I have all that are available including the New Testament.
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Reviewed in the United States on August 3, 2025
★★★★★ 5
Do get this translation.
Format: Paperback
We have purchased all that have been translated thus far. We really do like this translation to go with our ESV. The footnotes are tremendous.
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Reviewed in the United States on February 24, 2026
★★★★★ 5
HE IS THE BEST WRITER, AND GREAT REFERENCE NOTES, DETAILS FOR STUDY
Format: Paperback
I CAN'T GET ENOUGH OF BRIAN SIMMONS BOOKS. THESE ARE AMAZING, THE FOOTNOTES ARE INCREDIBLY DETAILED AND HELPFUL -- YOU WILL LEARN SO MUCH -- THE WRITING IS REALLY REVELATIONAL IN ITS STYLE -- I LIKE THIS PASSION TRANSLATION A LOT! BUYING UP ALL THE BOOKS AS THEY ARE RELEASED AND THE 12 STUDY GUIDES -- THEY ARE ALSO AMAZING -- YOU WILL ENJOY THE WAY HE HAS SET UP THE STUDY AS WELL -- USEFUL. AS I SAID, GO BUY THIS, IT'S REALY A NICE BOOK. I CAN HARDLY WAIT UNTIL HE HAS THE WHOLE BIBLE DONE SO I HAVE IT ALL IN A BIBLE WITH ALL THOSE GREAT FOOTNOTES AND DETAILS. KEEP WRITING BRIAN! AND THANK YOU AND YOUR TEAM FOR THE GREAT WORK YOU ARE DOING!
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Reviewed in the United States on January 1, 2025
★★★★★ 5
The Passion Translation
Format: Paperback
The Passion Translation is a great add for Bible Study! It gives more understanding and revelation into the writers of the time and God’s message to His people. I highly recommend The Passion translation for those looking to enhance their discipleship training.
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Reviewed in the United States on January 31, 2026