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For Your Every Summer RSVP, with Code: SUMMER15
Description
IL-15 hFc tag Protein, HumanProduct Specification Synonyms Interleukin 15, IL15 Accession P40933 Amino Acid Sequence Asn49 Ser162, with C hFc tag Expression System HEK293 Molecular Weight Predicted MW: 38. 8 kDa Observed MW: 45 60 kDa Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag Human Fc Tag Physical Appearance Lyophilized powder Storage Buffer 0. 2M PBS, pH7. 4. Reconstitution Reconstitute no more than 1 mg mL according to the size in deionized water
Product Specification
| Synonyms | Interleukin-15, IL15 |
| Accession | P40933 |
| Amino Acid Sequence |
Asn49-Ser162, with C-hFc tag
|
| Expression System | HEK293 |
| Molecular Weight |
Predicted MW: 38.8 kDa Observed MW: 45-60 kDa
|
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer |
0.2M PBS, pH7.4.
|
| Reconstitution |
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
|
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
|
Background
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 is constitutively expressed by a large number of cell types and tissues, including monocytes, macrophages, dendritic cells (DC), keratinocytes, fibroblasts, myocyte and nerve cells. As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.
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