Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 24 - Aug 29
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
FITC Mouse Anti-Human CD196 Antibody (S-R645)Product Specification Host Mouse Antigen CD196 Synonyms C C chemokine receptor type 6; C C CKR 6; CC CKR 6; CCR 6; Chemokine receptor like 3 (CKR L3); DRY6; G protein coupled receptor 29; GPR CY4 (GPRCY4); LARC receptor; CCR6; CKRL3; CMKBR6; GPR29; STRL22 Location Cell membrane Accession P51684 Clone Number S R645 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0.
Product Specification
| Host | Mouse |
| Antigen | CD196 |
| Synonyms | C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3 (CKR-L3); DRY6; G-protein coupled receptor 29; GPR-CY4 (GPRCY4); LARC receptor; CCR6; CKRL3; CMKBR6; GPR29; STRL22 |
| Location | Cell membrane |
| Accession | P51684 |
| Clone Number | S-R645 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD196, also known as CCR6, is a seven-transmembrane G protein-coupled receptor belonging to the beta-chemokine receptor family. It is expressed on B cells, subsets of T cells, dendritic cells, natural killer cells, and Langerhans cells. CD196 binds to its ligand CCL20 (MIP-3α) and plays a key role in regulating the migration and recruitment of immune cells, particularly in inflammatory and immune responses. Additionally, CD196 is involved in the differentiation of Th17 cells and the development of regulatory T cells (CD4+FoxP3+). In pathological contexts, CD196 is associated with various diseases, including autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease, as well as certain cancers.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy