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Description
TROP1/EpCAM His Tag Protein, MouseProduct Specification Species Mouse Synonyms TROP1, EpCAM, TACSTD1, CD326, DIAR5, EGP2, EGP314, EGP40, ESA, HNPCC8, HNPCC 8, KSA, M4S1, MIC18, MK1, GA733 2 Accession Q99JW5 Amino Acid Sequence Gln24 Thr266, with C terminal His Expression System HEK293 Molecular Weight 33 38kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at
Product Specification
| Species | Mouse |
| Synonyms | TROP1, EpCAM, TACSTD1, CD326, DIAR5, EGP2, EGP314, EGP40, ESA, HNPCC8, HNPCC-8, KSA, M4S1, MIC18, MK1, GA733-2 |
| Accession | Q99JW5 |
| Amino Acid Sequence | Gln24-Thr266, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 33-38kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Brunner A. et al. (2008) EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 61(3):307-310. 2、Trzpis M. et al. (2008) EpCAM in morphogenesis. Front Biosci. 13: 5050-5055. 3、Munz M. et al. (2009) The emerging role of EpCAM in cancer and stem cell signaling. Cancer Res. 69(14): 5627-5629. 4、Carpenter G. et al. (2009) EpCAM: another surface-to-nucleus missile. Cancer Cell. 15(3): 165-166. |
Background
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.
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4.4 ★★★★★
Based on 19 reviews
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Product Reviews
★★★★★ 5
Excellent Suit for the Money. Great, rich details.
Size: X-Large, Color: Black
This is a stunning piece of clothing. The material for the vests and pants are so luxurious and make it look like you spent a lot of money. Great versatility and thick material of great quality. The material is made of a rich fabric that feels subtle and gentle, but with the patterns showing well. It fits well and allows for movement. Whether you are looking for a wedding suit, or something to wear to a gala or bow-tie event, this is it.
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Reviewed in the United States on April 12, 2026
★★★★★ 5
Buy the suit. Be sure to measure!
Size: Large, Color: Red, Size: Large, Color: Red
Suit looks better than the photo in person. The suit is also made well. Great fabric and pattern!
My son is 6'1 and weighs around 135-140 pounds. I ordered a size large for him so the pants would be long enough. The pants were a little big but it was nothing a belt could not fix. The jacket and vest fit well too. The item also arrived on time.
***Suit runs small BUT if you take out time to do the measurements you will get the correct size.***
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Reviewed in the United States on February 16, 2026
★★★★★ 5
Great Buy
Size: Large, Color: Black
True to size. Material is nice and thick. Perfect attire for Wedding or any formal event.
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Reviewed in the United States on June 3, 2026
★★★★★ 4
Pants run small
Size: 3X-Large, Color: Purple
Jacket fit .. but pants did not. Nice suit though.
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Reviewed in the United States on May 28, 2025
★★★★★ 5
Fits like a glove, looks like a million!
Size: Small, Color: Purple
Bought this as a gift for him and very impressed. Looks like a million dollars, fit true to size, looks tailored not cheap. Fabric is quality, stitching is done well and the pants have a nice hidden elastic extender that helps if he goes up or down a few pounds. Very impressed!
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Reviewed in the United States on May 14, 2026