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Description
iNOS Recombinant Rabbit mAb (S-466-102)Product Specification Host Rabbit Antigen iNOS Synonyms inducible Nitric oxide synthase, Inducible NO synthase (Inducible NOS), Macrophage NOS (MAC NOS), NOS type II, Peptidyl cysteine S nitrosylase NOS2, Nos2, Inosl Immunogen Synthetic Peptide Location Cytoplasm Accession P29477 Clone Number S 466 102 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Ms, Rt Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | iNOS |
| Synonyms | inducible Nitric oxide synthase, Inducible NO synthase (Inducible NOS), Macrophage NOS (MAC-NOS), NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Nos2, Inosl |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P29477 |
| Clone Number | S-466-102 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:100 | |
| ICC | 1:500 | |
| IP | 1:50 | |
| ICFCM | 1:500 |
Background
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism.
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