SKU: 36656209990

SLU7 (N-acetyl-Ser2) Recombinant Rabbit mAb (S-3662-17)

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Description

SLU7 (N-acetyl-Ser2) Recombinant Rabbit mAb (S-3662-17)Product Specification Host Rabbit Antigen SLU7 (N acetyl Ser2) Synonyms Pre mRNA splicing factor SLU7; SLU7 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession O95391 Clone Number S 3662 17 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample HeLa, Jurkat, K562, HepG2 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.

Product Specification


Host Rabbit
Antigen SLU7 (N-acetyl-Ser2)
Synonyms Pre-mRNA-splicing factor SLU7; SLU7
Immunogen Synthetic Peptide
Location Cytoplasm, Nucleus
Accession O95391
Clone Number S-3662-17
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample HeLa, Jurkat, K562, HepG2
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
Dot Blot 1:1000
WB 1:1000 Hu

Background

SLU7 (N-acetyl-Ser2) protein refers to a specific post-translationally modified form of the SLU7 protein, a highly conserved splicing factor essential for the second catalytic step of pre-mRNA splicing in eukaryotes, where the designation "N-acetyl-Ser2" indicates that the serine residue at the second position of its N-terminus has undergone N-terminal acetylation, a common co-translational modification catalyzed by NatA complexes that often influences protein stability, subcellular localization, or interaction with other components of the spliceosome; while the core function of SLU7 involves stabilizing the active site conformation and facilitating the selection of the 3' splice site during exon ligation, this specific N-terminal acetylation may fine-tune its role within the dynamic spliceosomal machinery, potentially affecting its turnover rate or affinity for partner proteins like PRP18 and PRP22, although detailed functional distinctions solely attributable to this specific acetylation mark compared to the non-acetylated form remain an area of ongoing molecular investigation within the broader context of gene expression regulation.

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SKU: 36656209990

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Reviewed in the United States on January 18, 2026
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