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Description
HVEM/TNFRSF14 Recombinant Rabbit mAb (S-727-70)Product Specification Host Rabbit Synonyms Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, HveA, Tumor necrosis factor receptor like 2, TR2, CD270, HVEA, HVEM Immunogen Recombinant Protein Location Cell membrane Accession Q92956 Clone Number S 727 70 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC, FCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Synonyms | Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2, CD270, HVEA, HVEM |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q92956 |
| Clone Number | S-727-70 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC, FCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| ICC | 1:500 | null |
| FCM | 1:50 | null |
Background
Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily encoded by the TNFRSF14 gene. Mutations in this protein have been recurrently been associated to cases of diffuse large B-cell lymphoma and pediatric-type follicular lymphoma. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism.
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