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Description
Alexa Fluor® 700 Mouse Anti-Human CD14 Antibody (S-631-50)Product Specification Host Mouse Antigen CD14 Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell specific leucine rich glycoprotein Immunogen Recombinant Protein Location Secreted, Cell membrane Accession P08571 Clone Number S 631 50 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 05mg ml Conjugation Alexa Fluor 700 Physical Appearance
Product Specification
| Host | Mouse |
| Antigen | CD14 |
| Synonyms | Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein |
| Immunogen | Recombinant Protein |
| Location | Secreted, Cell membrane |
| Accession | P08571 |
| Clone Number | S-631-50 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human PBMC |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | Alexa Fluor® 700 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD14 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein primarily expressed on monocytes, macrophages, and some granulocytes. It functions as a pattern recognition receptor (PRR) and plays a crucial role in the innate immune response by recognizing bacterial lipopolysaccharides (LPS), pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs). CD14 exists in two forms: membrane-bound CD14 (mCD14) and soluble CD14 (sCD14), which can be secreted by activated cells. It acts as a co-receptor for Toll-like receptor 4 (TLR4) and enhances the immune response to LPS by facilitating its delivery to the TLR4-MD2 complex. Additionally, CD14 is involved in TLR4-independent signaling pathways and contributes to tissue homeostasis by promoting the clearance of apoptotic cells.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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- Please click here for more details>>> Return & Exchange Policy
4.3 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 5
Works Great! Very bright
My dog and I really love this ball. Bought this so we can play in the field behind our house at night. Tried other balls, like the glowing ones, but they're not bright enough. Other battery powered balls don't stay on long enough and I got tired of looking for them in the dark. This one stays on, depending on the switch setting, either 5 minutes, or indefinitely until it's shut off or until the battery dies. The battery, according to the instructions, should last 10 hours before needing recharging. I've charged it once when it was received, haven't had to re-charge it yet, played with it about 7 nights now 20 min each time and it's still going.
Others have said it's not very durable, but I've found it to be durable enough to play catch with our border collie, haven't had any issues. but I don't let him chomp on it all he wants, just throw it and he brings it back. I suppose if your dog is an aggressive chewer and you let him just sit there and go to town on it, it won't last very long, just like any other ball. We use this ball only at night when needed, and use cheaper balls at other times to increase its life span.
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Reviewed in the United States on December 19, 2024
★★★★★ 5
THIS IS A MUST-BUY! If you have a dog--you NEED this ball!
Color: Orange
We have two 18-month-old chocolate Labs (brothers—basically twins with paws). The best time to walk them is early morning or just before dark… which is exactly how we managed to lose approximately 9,472 tennis balls in our cornfield. RIP, brave yellow soldiers.
So I went searching for a ball that didn’t just glow—I wanted one that full-on lights up like a tiny dog disco. Enter this LED ball. Game. Changer.
Our walks are now way more fun. The ball bounces, flashes, and changes colors like it’s auditioning for a rave. People literally slow their cars as they drive past our field just to watch the light show. I’m not saying we’re local celebrities now… but I’m not not saying that either.
And here’s the real magic: when the boys get distracted and abandon the ball (because squirrel), it stays lit so I can actually find it. We also bought a ball launcher from Walmart for about $9, and the LED ball fits perfectly—same size as a tennis ball, just 100x cooler.
This ball is waterproof and mostly floats, although I haven’t been brave enough to throw it into the pond or river because I’m positive my dogs would treat that as a full-scale navy search mission and never find it again.
It’s easy to charge, and even with 2–3 hours of walking daily, I only have to plug it in every few weeks. We’ve had it for months now and it’s still going strong—super durable. We don’t let them chew on it off-walk (because Labs), but during fetch? It’s a champ.
Also—small but hilarious detail—when they catch it, their mouths light up. I have accidentally created glow-in-the-dark dogs.
I love this ball so much I’m buying a backup because life without it is not an option. Best dog toy EVER. Whoever invented this deserves a medal, a parade, and a lifelong supply of tennis balls they’ll never lose again. 🐾💡
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Reviewed in the United States on December 1, 2025
★★★★★ 1
DISAPPOINTED
Color: Blue
only lasted 3 months after about a dozen uses. The LED core fell out and now it's totally useless. Not worth the cost at all. Disappointed because my dogs really loved them.
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Reviewed in the United States on March 26, 2026
★★★★★ 5
Dog is obsessed with this.
The spa works as intended it lights up at night, which is super helpful for short winter days and for when the snow starts to pile up, it illuminates the snow pile that dog dropped it in so I can find it. I haven’t actually charged it yet. It came fully charged and has been in use for over a week without needing a recharge. We only use it on outside excursions together. I keep it in my pocket on walks in case he needs something in his mouth or an incentive to run a little off leash. I like that there are two settings to the light which I didn’t notice when I ordered it. One will shut off after five minutes of inactivity to save battery, which is really convenient so I don’t have to keep on screwing it to turn it on and off or there’s a second setting where the light stays on until you manually turn it off. We have it on the battery saving mode and we have never lost it. Overall, a really fun toy that even the neighbors, tiny dog who can barely pick it up and enjoys. It’s not really soft for like chewing, but that also means he’s not going to destroy it. It is a heavy ball to throw, but not too bad. One of my favorite purchases for this puppy.
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Reviewed in the United States on January 19, 2025
★★★★★ 3
Great while it lasted
Color: Blue, Color: Blue
This ball is great for my 13 year old low eyesight Boston terrier at night but after Less then a month of playing the inside of the ball falls out.
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Reviewed in the United States on May 20, 2026
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