Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 6 - Sep 11
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
NMT1 Recombinant Rabbit mAb (S-2986-17)Product Specification Host Rabbit Antigen NMT1 Synonyms Glycylpeptide N tetradecanoyltransferase 1; Myristoyl CoA: protein N myristoyltransferase 1 (HsNMT1; NMT 1; Type I N myristoyltransferase); Peptide N myristoyltransferase 1; Protein lysine myristoyltransferase NMT1; NMT Immunogen Synthetic Peptide Location Cytoplasm Accession P30419 Clone Number S 2986 17 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt, Mk
Product Specification
| Host | Rabbit |
| Antigen | NMT1 |
| Synonyms | Glycylpeptide N-tetradecanoyltransferase 1; Myristoyl-CoA:protein N-myristoyltransferase 1 (HsNMT1; NMT 1; Type I N-myristoyltransferase); Peptide N-myristoyltransferase 1; Protein-lysine myristoyltransferase NMT1; NMT |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P30419 |
| Clone Number | S-2986-17 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | SK-OV-3, HeLa, NIH/3T3, mouse brain, COS-7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms, Mk |
| IHC-P | 1:1000 | Hu, Ms, Rt |
Background
NMT1 is a cytosolic monomeric enzyme that catalyzes the irreversible, co-translational transfer of myristic acid from myristoyl-CoA to the N-terminal glycine of nascent polypeptides, a modification essential for membrane targeting, signal transduction, and stability of oncogenic kinases (e.g., Src, FAK), and its overexpression in cancers promotes proliferation, suppresses autophagy, and supports metabolic reprogramming through specific regulation of AMPKβ myristoylation, making it a validated therapeutic target.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy