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Description
Ly6G Recombinant Rabbit mAb (S-2495-6)Product Specification Host Rabbit Antigen Ly6G Synonyms Lymphocyte antigen 6G; Ly 6G; Ly 6G. 1; Ly6g Immunogen Synthetic Peptide Location Cell membrane Accession P35461 Clone Number S 2495 6 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Ms Positive Sample mouse bone marrow, mouse spleen, mouse lung Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS,
Product Specification
| Host | Rabbit |
| Antigen | Ly6G |
| Synonyms | Lymphocyte antigen 6G; Ly-6G; Ly-6G.1; Ly6g |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P35461 |
| Clone Number | S-2495-6 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Ms |
| Positive Sample | mouse bone marrow, mouse spleen, mouse lung |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms |
| IHC-P | 1:1000 | Ms |
| IF | 1:100 | Ms |
Background
Ly6G (Lymphocyte antigen 6 complex locus G6D) is a 21-25 kDa glycosylphosphatidylinositol (GPI)-anchored protein that belongs to the Ly-6 superfamily and is expressed in a developmentally regulated manner by myeloid cells, including neutrophils, granulocytes, and some monocytes. It serves as a key marker for mature neutrophils and is widely used in research to identify and deplete these cells in vivo. Ly6G is transiently expressed on monocytes during bone marrow development, while its expression on granulocytes and peripheral neutrophils correlates with their differentiation and maturation levels. This antigen plays important roles in immune responses, such as antitumor immunity and neutrophil-mediated inflammation.
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