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Description
Biotinylated CD47 His Tag Protein, HumanProduct Specification Species Human Synonyms Antigenic surface determinant protein OA3, CD47 antigen, CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47, Integrin associated protein, leukocyte surface antigen CD47 Accession Q08722 Amino Acid Sequence Gln19 Pro139, with C terminal His&Avi Tag Expression System HEK293 Molecular Weight 30 35 kDa(Reducing) Purity 95%, by SDS PAGE under reducing conditions Endotoxin <0. 2EU g Conjugation Biotin Tag His
Product Specification
| Species | Human |
| Synonyms | Antigenic surface determinant protein OA3, CD47 antigen, CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47, Integrin-associated protein, leukocyte surface antigen CD47 |
| Accession | Q08722 |
| Amino Acid Sequence | Gln19-Pro139, with C-terminal His&Avi Tag |
| Expression System | HEK293 |
| Molecular Weight | 30-35 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.2EU/μg |
| Conjugation | Biotin |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS pH7.2, 5% trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
CD47 (Cluster of Differentiation 47), also known as integrin associated protein (IAP), is a transmembrane protein that in humans is encoded by the CD47 gene. It belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. Also CD47 is ubiquitously expressed in human cells and has found to be overexpressed in many different tumor cells.
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