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Description
PELP1 Recombinant Rabbit mAb (S-756-22)Product Specification Host Rabbit Synonyms Proline , glutamic acid and leucine rich protein 1, Modulator of non genomic activity of estrogen receptor, Transcription factor HMX3, HMX3, MNAR Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q8IZL8 Clone Number S 756 22 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Synonyms | Proline-, glutamic acid- and leucine-rich protein 1, Modulator of non-genomic activity of estrogen receptor, Transcription factor HMX3, HMX3, MNAR |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q8IZL8 |
| Clone Number | S-756-22 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| ICC | 1:500 | |
| ICFCM | 1:500 | |
| IP | 1:50 |
Background
Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) is transcription coregulator and modulates functions of several hormonal receptors and transcription factors. PELP1 plays essential roles in hormonal signaling, cell cycle progression, and ribosomal biogenesis. PELP1 expression is upregulated in several cancers; its deregulation contributes to hormonal therapy resistance and metastasis; therefore, PELP1 represents a novel therapeutic target for many cancers.
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