SKU: 11464464512

IL-21 Recombinant Rabbit mAb (SDT-768-207)

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Description

IL-21 Recombinant Rabbit mAb (SDT-768-207)Product Specification Host Rabbit Antigen IL 21 Synonyms Interleukin 21 Immunogen Recombinant Protein Accession Q9HBE4 Clone Number SDT 768 207 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against IL 2 Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300 Stability & Storage 12 months from

Product Specification


Host Rabbit
Antigen IL-21
Synonyms Interleukin-21
Immunogen Recombinant Protein
Accession Q9HBE4
Clone Number SDT-768-207
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against IL-2
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

Interleukin-21 (IL-21) is a four-α-helical-bundle type I cytokine produced mainly by activated CD4⁺ T helper cells, NKT cells and TFH cells that signals through a heterodimeric receptor composed of the IL-21R and the common γ-chain (γc) to activate JAK1/JAK3–STAT1/STAT3 pathways, thereby orchestrating a broad immunomodulatory program that drives the differentiation, proliferation and effector function of B cells into long-lived plasma cells and memory B cells, promotes the development of Th17 and Tfh subsets while suppressing Treg stability, enhances cytotoxic activity and survival of CD8⁺ T cells and NK cells, and synergizes with IFN-γ or IL-15 to amplify antiviral and antitumor immunity, making it a key molecular hub whose dysregulation contributes to autoimmune pathologies such as systemic lupus erythematosus and type 1 diabetes and whose exogenous delivery or blockade is being therapeutically exploited in cancer immunotherapy, chronic viral infections and allergy.

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SKU: 11464464512

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4.2 ★★★★★
Based on 23 reviews
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Verified Purchase
Julie G
Lake Worth, US
★★★★★ 5
The only thing that works for me
Size: 50 count (Pack of 1)
I love these face wipes so much. I cannot use soap due to all the problems I have with my skin. It's so finicky.. I have rosacea with painful P&P and also flare ups of adult acne. I take a med to keep my oil production under control, but that means I end up with a few flakey patches on my cheeks. These are the ONLY face wipes that I've found that not only remove almost all (more on that in a moment) of the makeup I'm wearing, but also seem to help keep my redness under control. I've tried Aveeno Ultra-Calming wipes which profess to help with redness and even those are way too harsh for my skin. The Aveeno wipes make my face sting horrible, leave a greasy residue, and have a smell that is not very pleasant. The Simple wipes take off WAY more makeup than those, or any other wipe, I've tried and leave my skin feeling actually clean and calm. The only routine that I've found that keeps my skin looking decent is to use these to remove the majority of my makeup and then follow up with Simple Micellar Water on a cotton pad to remove any further traces. I follow that up with a few spritzes of (rosewater is supposed to help with redness too) and then moisturize with - which doesn't have SPF (which makes my rosacea flare up). It sounds like a lot of steps, but it takes me 3 minutes, tops. I'd just like to add too for those saying that these don't remove waterproof mascara - well, yeah. I would want neither a "gentle" face wipe that was harsh enough to remove waterproof mascara, nor a mascara that was wimpy enough to be removed with a gentle wipe... that would mean it would also come off every time my eyes watered or even just blinked. Just use an oil-free eye makeup remover before using these.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 2, 2016
N
Verified Purchase
Nicole Quashie
Louisville, US
★★★★★ 5
great clean.
Size: 50 count (Pack of 1)
These get my face clean and exfoliated. I love them.
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Reviewed in the United States on April 2, 2026
G
Verified Purchase
Gina
Lexington, US
★★★★★ 5
The best makeup wipes
Size: 50 count (Pack of 1)
The best makeup wipes- soft and fast and they smell great!
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Reviewed in the United States on February 5, 2026
M
Verified Purchase
Martha
Draper, US
★★★★★ 5
Just love these and they are sometimes hard to find.
Size: 50 count (Pack of 1)
These are great they make you skin feel fresh. They never irritate my face. Always you one before moisturizer.
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Reviewed in the United States on April 5, 2026
P
Verified Purchase
Pearlh
Los Angeles, US
★★★★★ 4
Work well, no bad skin reactions
Size: 50 count (Pack of 1), Size: 50 count (Pack of 1)
I can't believe what a great deal these are! It's less than $7 (as an add-on buy) for two packets. I had already bought this brand once before so I knew they'd work for me. They remove make-up pretty well. I don't think they are the very best of all time, but they are up there with the other brands I've tried. This product states that it has no artificial dyes or perfumes. These points are really important. Any fragrance that is added to beauty products can irritate your skin, which has happened to me in the past. I do detect the slightest scent, though. It's actually rather pleasant. I think there's still a slight residue of mascara left over after using the wipes pretty thoroughly, so I only gave them 4 stars. Your experience may differ as the packaging promises to remove all makeup residue. Maybe I'm not using them properly? I have very sensitive skin and I didn't break out or otherwise react poorly to these. They do the job as well as I think can be expected for facial wipes so I bought them again. I really hope the claims to being simply formulated are true. I have a healthy scepticism of the beauty industry. My experience with these wipes has been positive so I will take it on faith that they live up to their advertising as far as having no unnecessary additives. One more thing: I like the idea of the added vitamins. It always cracks me up when facial cleansers advertise the addition of helpful vitamins. How can they help when you're immediately rinsing them back off your face? The addition of any vitamins to regular liquid cleansers is just a waste. They do nothing for you. That being said, when they are added to facial wipes, they are spread on your skin and stay there, since you don't generally rinse after using wipes. In this way of cleaning, you may actually be reaping some benefit from the added vitamins.
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Reviewed in the United States on July 18, 2016

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