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Description
CD1d Recombinant Rabbit mAb (S-2686-138)Product Specification Host Rabbit Antigen CD1d Synonyms Antigen presenting glycoprotein CD1d; R3G1; CD1D Immunogen Recombinant Protein Location Cell membrane, Endoplasmic reticulum membrane Accession P15813 Clone Number S 2686 138 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample Jurkat, Molt 4 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS,
Product Specification
| Host | Rabbit |
| Antigen | CD1d |
| Synonyms | Antigen-presenting glycoprotein CD1d; R3G1; CD1D |
| Immunogen | Recombinant Protein |
| Location | Cell membrane, Endoplasmic reticulum membrane |
| Accession | P15813 |
| Clone Number | S-2686-138 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | Jurkat, Molt-4 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
Background
CD1d is a transmembrane glycoprotein that belongs to the group 2 CD1 family of non-classical MHC class I-like antigen-presenting molecules, expressed on dendritic cells, thymocytes, hepatocytes and many other tissues; it forms a heterodimer with β2-microglobulin, folds into a deep, hydrophobic groove made up of A′ and F′ pockets that cradle lipid tails while exposing the glycosyl headgroups of self or microbial glycolipids, and delivers these antigens to the invariant T-cell receptor of CD1d-restricted natural killer T (iNKT) cells, thereby rapidly triggering large bursts of cytokines such as IFN-γ and IL-4 that shape innate and adaptive immune responses against infections, cancer, and autoimmune diseases .
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Exchange/Return Notes
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