Pay in installments of $56.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 19 - Sep 24
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Anti-CD163 Antibody (OR2805)Product Specification Host Human Antigen Antibody (OR2805) Synonyms Scavenger receptor cysteine rich type 1 protein M130; Hemoglobin scavenger receptor; M130 Location Secreted, Cell membrane Accession Q86VB7 Clone Number OR2805 Antibody Type Recombinant mAb Isotype IgG1,k Application ELISA Reactivity Hu Purification Protein A Concentration 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12
Product Specification
| Host | Human |
| Antigen | Antibody (OR2805) |
| Synonyms | Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor; M130 |
| Location | Secreted, Cell membrane |
| Accession | Q86VB7 |
| Clone Number | OR2805 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1,k |
| Application | ELISA |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
OR2805 is a fully human IgG1 monoclonal antibody that targets CD163, an immune-suppressive receptor highly expressed on tumor-associated macrophages (TAMs) within the tumor microenvironment. This antibody was discovered using B cells from an elite responder to checkpoint inhibitor therapy. It has the potential to relieve immunosuppression caused by M2c macrophages, thereby enhancing anti-tumor T-cell responses. In preclinical studies, OR2805 demonstrated significant anti-tumor activity in lung cancer xenograft models and did not trigger the release of major cytokines in human whole blood. Currently, it is being evaluated in clinical trials as a potential cancer immunotherapy, both as a monotherapy and in combination with checkpoint inhibitors.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy