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Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.7 ★★★★★
Based on 25 reviews
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Product Reviews
★★★★★ 5
Great little sprayer
Size: 1-Gallon
This thing works really well. My only complaint is that you can't really get a tight cone on the mist setting. I wanted to be a little more precise, but it still got the job done. I would recommend this more for lawn treatments over bug spray (which is what I used it for), just because of the wide dispersal cone (especially indoors). However, it still works just fine, and gives a lot of coverage in a short amount of time. It does shoot a very precise stream out, but it's way too much liquid at once in my opinion. If you're wanting precision, you'll need to look elsewhere. As for the value, it's well worth it.
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Reviewed in the United States on May 25, 2026
★★★★★ 5
Chapin 1-gallon sprayer
Size: 1-Gallon, Size: 1-Gallon
★★★★★ Versatile Little Sprayer That’s Great Around the House, Garden & Garage.
This Chapin 1-gallon sprayer has turned out to be one of the handiest tools I own. I originally bought it for spraying organic bug treatment and neem oil mixtures on my plants and garden, but I’ve ended up using it for several different things.
The pump builds pressure quickly and the spray pattern adjusts easily from a fine mist to a stronger stream depending on what you’re doing. It sprays evenly and feels much more controlled than some of the cheaper sprayers I’ve tried in the past.
One thing I like is keeping separate sprayers for different jobs. I use this one mainly for garden and plant care, while I keep another one strictly for bug spray and outdoor treatments so chemicals don’t get mixed together.
It’s also useful outside the garden. You could easily use this for automotive detailing too — things like liquid waxes, degreasers, wheel cleaners, or spray-on protectants. The wand and hose feel durable, and the tank itself feels sturdy without being too heavy to carry around.
Simple, reliable, easy to clean, and useful for way more than just gardening. Definitely worth having around the house or garage.
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Reviewed in the United States on May 16, 2026
★★★★★ 4
Works well. Easy to carry.
Size: 1-Gallon 2-Value Pack
My 2-gallon sprayer’s nozzle cracked — leading to Spectracide dribbles along my path through the yard…not good!
Since a replacement nozzle cost as much as a new sprayer, so began the search for a new unit. I admit that lugging a full 2-gal sprayer around the yard, although it required no refilling, became quite tiring and blister-inducing; I then began reading reviews for 1-gal …
Horror stories about bad seals, leaks, no pressure, etc. had me dismayed. However, since Amazon’s return policy is easy, I decided on this 2-pack of 1-gal Chapin 22000. If needing my usual 1.5-2 gallons of weed killer, I could always fill BOTH ahead of time and save myself some blisters and backache!
Never having used pressurized sprayers WITHOUT pressure relief valves, I was slightly hesitant to buy these, though…well, I guess I’ll just have to be extremely careful to not get the poisonous spray on myself when removing the pump! ☠️
Sprayers arrived in perfect, brand new condition; all parts/pieces were received. Assembly was super easy, even WITHOUT referring to instruction manual — used channel locks to tighten the hose, as pliers could not be located and hands are not very strong. Tested/practiced with water. Got a feel for how many pumps were necessary and adjusted the spray tip to my preference.
My last sprayer required opening the PRV and then squeezing sprayer to empty hose/release remaining pressure in order to be able to unscrew pump handle. The directions for THESE say to simply unscrew the handle a bit until you can hear the built-up pressure vent out. I did just that — no explosive spray to the face and the pump handle unscrewed easily. WHEW!
So, today was the sprayer’s maiden voyage around the yard.
I followed the directions to pump the handle until resistance is felt (maybe 8x?). WOW — so much easier to carry! Pressure is great — liquid shot out about 15’! Although the “feel” of the sprayer trigger is cheap and small (even for female hands), it was quite responsive and allowed for a steady stream with no leaks/dribbles.
Happy with this purchase and hope I can get at least a few years out of them. 🤞🏼
Also, after I’d placed my order, I just happened to be in WM’s lawn/garden section…
These are sold there, as well, for a higher price. They seem to be very popular, too, as nearly all were gone from the shelf.
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Reviewed in the United States on April 1, 2026
★★★★★ 5
Simple, Reliable Pump Sprayer with Easy Locking Trigger
Size: 1-Gallon
This pump sprayer is very straightforward to set up and gets ready for use quickly without any complicated assembly. The locking trigger is a standout feature since it allows continuous spraying without needing to constantly hold the handle down, which makes longer watering or treatment tasks much easier on the hand. The spray output feels consistent and controlled, and it works well for garden applications like fertilizer, herbicide, or general watering. The build quality feels solid enough for regular home and garden use, and the tank is easy to fill and pressurize without much effort. The handle and pump action feel smooth, and overall operation is simple and intuitive. Considering the ease of use, practical locking trigger, quick setup, and reliable performance, it offers good value for the money for everyday garden and yard maintenance tasks.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Solid product at affordable price
Size: 1-Gallon
It’s working well so far after a couple spraying with it; easy to assemble; good delivery, good price. It’s a good one to get for spraying foliage in your yard.
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Reviewed in the United States on May 14, 2026