SKU: 30407547513

텔미온정( Hypertension )

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Description

텔미온정( Hypertension )1. 1) : 6 2 2) : 1 2 . 2 1 2. . . , . . . 1. 1) : , . 2 1 3 ( 5. ). , . . (17 ) : 1 25 . , 1 2 1 25 50 1 2 , , . . 1 100200mg. 1 500. 1 1,000 . (6 16) : 1 0. 5 1 . 1 2 1 0. 5 1 1 2 , , , . . 1 3 6mg kg. 1 500 . 2) (17 ) : 1 200mg 1 200 400mg 2 . 1 800mg . 1 25 50mg , . 1 2 25 50mg 1 2 . . . (2 16) : 1 5 9mg kg, 1 2 . 1 25mg( , 1 1 3mg kg ) , 1 2 1 1 3mg kg 1 2 . . 1 30mg kg , . 2. : 1 25mg . 1 25mg . , . 1 100mg 1 2 . 1 50mg . 1 200mg , . 3. (CLcr <

효능효과

1. 뇌전증

1) 단독요법 : 6세 이상의 소아 및 성인에서의 2차성 전신발작을 동반하거나 동반하지 않은 부분발작 치료

2) 부가요법 : 기존 1차 항뇌전증약 투여로 적절하게 조절이 되지 않는 2세 이상의 소아 및 성인에게서 다음 질환에 사용된다.

- 2차성 전신발작을 동반하거나 동반하지 않은 부분발작

- 레녹스-가스토 증후군과 관련된 발작

- 1차성 강직성/간대성 전신발작

2. 편두통의 예방

용법용량

이 약은 낮은 용량에서 시작하여 유효용량까지 증량하는 것이 바람직하다.

이 약의 투여를 최적화하기 위해 혈중농도를 모니터할 필요는 없다.

이 약의 권장용량은 신장질환이 없는 경우, 노인을 포함한 모든 성인 및 소아에게 그대로 적용한다.

식사와 관계없이 투여할 수 있다.

정제는 부수지 말고 그대로 복용해야 한다.

1. 뇌전증

1) 단독요법 : 단독요법으로 토피라메이트를 투여하기 위해 병용중인 다른 항뇌전증약을 중단할 경우, 발작조절에 미칠 수 있는 영향을 고려해야 한다. 안전성 문제로 다른 항뇌전증약을 즉시 중단해야 하는 경우를 제외하고는 2주 간격으로 다른 항뇌전증약을 1/3정도로 단계적으로 감량 중단하도록 한다(사용상 주의사항 “5. 일반적 주의”항 참조).

약물대사 효소 유도 약물을 중단시, 토피라메이트 농도가 상승할 수 있다. 만약 임상적으로 토피라메이트의 농도 상승이 나타날 경우 이 약의 용량을 감량할 필요가 있다.

- 성인 (17세 이상) :

처음 1주일 동안 저녁에 25㎎씩 투여를 시작한다. 이후, 1-2주 간격으로 1일 25 또는 50㎎씩 증량하여 1일 2회로 나누어 투여하도록 하며, 만약 환자가 이러한 증량 경과를 견디기 어려워지면, 증량간격을 길게하도록 한다. 용량이나 증량속도는 임상적 반응에 따라 결정한다. 성인에 대한 단독요법으로서의 권장용량은 1일 100~200mg이다. 최대 권장용량은 1일 500㎎이다. 재발된 뇌전증 환자 중 일부는 토피라메이트 단독요법시 1일 1,000㎎까지 내약성이 있었다.

- 소아(6-16세) :

처음 1주일 동안은 저녁에 0.5-1㎎/㎏으로 투여를 시작한다. 이후 1-2주 간격으로 1일 0.5-1㎎/㎏씩 증량하여 1일 2회 투여하도록 하며, 만약 환자가 증량을 견디기 어려워하면, 증량단위를 줄이거나, 증량간격을 늘리도록 한다. 용량이나 증량정도는 임상반응에 따라 결정한다.

소아에 대한 단독요법으로서의 권장용량은 1일 3-6mg/kg이다. 부분발작으로 진단된 소아의 경우 1일 500㎎까지 투여한 경험이 있다.

2) 부가요법

- 성인(17세 이상) :

최소유효량은 1일 200mg이며 통상 1일 200-400mg을 2회로 나누어 투여한다. 환자에 따라 최대 권장용량인 1일 800mg까지 투여할 수 있다. 처음 1주일 동안은 저녁에 25-50mg씩 투여하는 것으로 치료를 시작하며, 더 낮은 용량에서 시작하는 것도 가능하다. 이후에는 1-2주 간격으로 용량은 25-50mg씩 증량하여 1일 2회로 나누어 투여한다. 만약 환자가 증가용량을 견디기 어렵다면 더 적은 용량을 증가시키거나 증량 간격을 연장시킬 수 있다. 투여량은 임상효과에 따라 결정하여야 한다.

- 소아(2세-16세) :

1일 권장용량은 약 5-9mg/kg이며, 1일 2회로 나누어 투여한다. 처음 1주일 동안은 25mg(또는 그 이하, 1일 1-3mg/kg을 기준으로 함)을 저녁에 투여하고, 이후에는 적절한 임상효과가 나타날 때까지 1-2주 간격으로 1일 1-3mg/kg씩 증량하여 1일 2회로 나누어 투여한다. 용량 적정은 임상효과에 따라 결정하여야 한다. 1일 30mg/kg까지 투여된 경우도 있으며, 이 경우 일반적으로 내약성이 좋았다.

2. 편두통의 예방

성인 : 처음 1주일 동안은 저녁에 이 약 25mg으로 투여를 시작한다. 이후 1주 간격으로 25mg/일 씩 증량한다. 만약 환자가 이러한 증량을 견디기 어려워하면, 증량간격을 길게 하도록 한다. 1일 권장용량은 100mg으로 1일 2회로 분할하여 투여하도록 한다. 일부 환자에서는 1일 50mg 용량에서도 효과를 나타낼수 있다. 1일 200mg까지 투여할수 있으며, 용량 및 증량 속도는 임상반응에 따라 결정 하도록 한다.

3. 신장애 환자

- 중등도 및 중증 (CLcr < 70 mL/min/1.73 m2)의 신장애 환자는 시작용량 및 유지용량의 약 1/2로 감량하는 것이 권장된다.

- 혈액투석환자: 이 약은 혈액투석으로 혈장에서 제거되기 때문에 혈액투석환자는 투석 당일에 이 약 투여용량을 약 1/2 증량한다. 투석에 걸리는 시간, 투석장치의 청소율 및 투석환자의 신청소율 등을 고려하여 투여량을 증량하고, 혈액투석의 시작과 종료 시에 분할 투여한다.

4. 간장애 환자

간장애 환자들은 이 약의 클리어런스가 감소될 수 있으므로 주의하여 투여하여야 한다.

포장단위

30정/병

저장방법

기밀용기, 25℃이하, 건소보관

사용기간


제조일로부터 36 개월

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SKU: 30407547513

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4.8 ★★★★★
Based on 10 reviews
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Product Reviews
C
Verified Purchase
Chay
Omaha, US
★★★★★ 5
Great for Tough chewers!
Size: Large, Color: Dinos Frills (Red)
My dog is a tough chewer and absolutely loves this toy! He was able to get a little stuffing out of the leg so far and it’s been about a week. This might sound like a short amount of time but it usually takes him under 15 mins to unstuff a large toy even if they are advertised for “tough chewers!” This is a very large size toy and would be good for any larger breed. He carries it around the house and constantly keeps his Dino with him. Since Ive found GoDog toys I’ve only been purchasing them because of their durability. I’ve tried Kong and Bark toys previously and they just do hold up long and are usually more expensive. This toy is a great value and dogs love them!
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Reviewed in the United States on October 20, 2025
G
Verified Purchase
Gerry
Massapequa, US
★★★★★ 5
Super cool strong dog toy!
Size: Large, Color: Dinos Frills (Red)
Super cool strong dog toy!
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Reviewed in the United States on May 12, 2026
M
Verified Purchase
MalinoisLover
Phoenix, US
★★★★★ 4
LOVE this brand. Have many of their styles. This is basically an unstuffed toy.
Size: Large, Color: Dinos Frills (Gray)
I have about 10 -12 different styles of the GoDog brand toys. It is like Xmas when my Malinois dogs get a new GoDog toy. Have loved this brand for many years and have some toys which have lasted 5-6 years -- minor "surgeries" stitch they back together -- until I retired them. They have never just worn out. Just to be clear: THESE TOYS ARE NOT CHEW PROOF. NO STUFFED TOY IS CHEW PROOF. However, this brand of stuffed toy is more chew proof than other brands. But if you are looking for a chew proof stuffed toy be advised -- IT DOES NOT EXIST!! No fabric is chew proof. Even if they invented such a fabric I would not want to ruin my dog's teeth by letting them try to chew through it. Protecting one's dog's teeth should be the highest priority. If a dog can chew through a PLASTIC KENNEL and even METAL WIRE KENNELS (yes, it happens) then they can easily chew through a puffy, fluffy stuffed toy. The "Chew Guard Technology" language may be misleading to some customers who are disappointed in the brand. I defend the brand and have used it for many years. No, I don't get paid or get free toys. Since I have had many styles within this brand and even have the pink version of this style I thought I knew what I was getting. This is basically a toy without stuffing which some people prefer. For whatever reasons my dogs prefer toys that are stuffed. Really stuffed with a firm density that they can sink their teeth into. So this toy will be OK. I can tell it will not be one of their beloved toys like some of the brand's other styles such as the purple brontosaurus. My fault for not reading more closely and assuming the grey version would be exactly like the pink version which is fully stuffed. If they get bored with these two I keep some of the Chew Guard toys stock piled. BTW one can wash and dry these toys. Yes, eventually the squeakers suck up some water and die but one can replace the squeakers. Also on Amazon. So I am willing to replace the squeakers a few times in the life time of one of these toys to be able to wash and dry them occasionally. Usually takes a couple drying cycles to get the heavily stuffed toys dried completely. If you have an aggressive chewer you may wish to look into Goughnuts dog toys or other hard rubber toys that are designed for aggressive chewers. Even then, with a determined dog, the Goughnuts toys can be chewed through. I think they offer a replacement guarantee. The other brand which has some toys of hard rubber is West Paw. An excellent brand that also offers a one time replacement. Bully Sticks are another option for chewers. PLEASE, PLEASE, PLEASE stay away from the hard plastic chew toys like the Nyla Bones. Hard plastic toys will destroy your dog's teeth over time. I learned the hard way (no pun intended) and ruined one of my dog's teeth. Vet asked if I allowed my dog to chew ROCKS !!!!!! Every tooth was cracked or fractured. Not wishing to pull teeth I had to pay for some very expensive root canals and caps. Vet's advise: If you can't dent the toy or chew with your finger nail DO NOT offer to your dog. Good advise to follow. Even some of the Bully Sticks (Costco Brand) are so hard they can chip or fracture teeth. Best for you and your dog.
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Reviewed in the United States on September 1, 2019
P
Verified Purchase
P SD
Phoenix, US
★★★★★ 5
Well made, minor issue was quickly resolved
Size: Large, Color: Dinos Bruto (Purple)
I purchased the Dino Bruto Dog toy for my labradoodle who is quite fond of squeaky, squawky stuffed toys and oddly enough has shown a preference for purple. I opened the package with my hound standing by waiting for his gift. I detached the tags and attempted to squeak the toy. It seemed difficult to squeak or honk. I tossed the purple Dino Bruto to my dog who excitedly chomped to squeak. The toy squawked a couple times and then just quit. My poor hound was staring up at me with that "what's up with this" look on his face. I tracked down the website for the GoDog toys, not going through the Amazon return process. I called the good people at GoDog and stated simply that my dog's favorite part of the toy failed quite quickly and I was wondering about guarantees. I was told to go to the website and file a replacement request. The replacement request required that I include a photo which I did as directed. I received an reply email within a couple hours which stated that a new toy would be sent out shortly. I am happy to report that we received a replacement toy, not the purple Dino, but a colorful wood duck. The squawker device works well and is still performing like new more than a month later. It appears that the squeaker is not those little plastic squeakers but the bigger heavy plastic bag, bladder, with what I visualize as a duck call sort of sound device. I am guessing because I haven't seen the inside of the GoDog toys. I have seen the guts of other stuffed toys which use this type of noise device. While our dog seems to enjoy the sound of the plastic bag, bladder set-up squawkers, they seem to fail quickly and I tend to avoid them because of this. The toys using this type of squawker that I have seen, use what looks like a cheap lightweight plastic bag which is not securely attached to the "voice box". Since the GoDog replacement toy is holding up so well, I am guessing GoDog uses a heavier grade plastic bladder coupled with reinforced construction. The purple Dino Bruto toy still looks new even after multiple times of our hound grabbing the purple toy, shaking it at us with his invite to give chase or play keep away. Since the squawker failed so quickly with the new toy, I figure it was just a defective item which does not reflect the general quality of toys from GoDog. One evening our neighbor was visiting while his pitbull was playing in our yard with our dog. Our patio door was open so our dog ran into the house and grabbed his purple Dino Bruto toy. He is a bit of a show-off with new toys. Our dog then went racing back into the yard, shaking his GoDog toy at the pitbull. A quick game of tug-of-war ensued. Since this is a new toy, our neighbor leaped into the game and took the toy away from the dogs. In that short time of tugging between the dogs, the toy held together and did not even pull apart at any of the seams. There were no puncture marks either. This is a game our dog has initiated before with the neighbor pitbull. Normally, the stuffed toys are ripped apart almost immediately. I was surprised and impressed with the quality of the sewing which appears to employ some sort of reinforced construction or heavier material. I plan to make more purchases from GoDog toys. The toys are a little more expensive than some stuffed dogs toys but they hold up so well I figure they are worth a few more dollars. They are great toys that hold up well and the company provides quick responses to inquiries. I consider this a winning combination.
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Reviewed in the United States on June 15, 2013
J
Verified Purchase
Jan F.
San Leandro, US
★★★★★ 5
Good quality
Size: Large, Color: Dinos Frills (Gray)
we’ve had many godog toys over the years and although my dog eventually rips through them I do find that they last longer than other cheap toys. Overall very well made!
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Reviewed in the United States on May 11, 2026

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