SKU: 19773956515

Core Nutritionals 5-AT

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Description

Core Nutritionals 5-AT5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex

5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

1. Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
2. Preventing muscle protein synthesis.
3. The breakdown of glycogen (the compound responsible for that “full look”).
4. Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol: In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

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SKU: 19773956515

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4.7 ★★★★★
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Justice
Omaha, US
★★★★★ 4
Soft Material, but Color Not as Expected
Size: Queen, Color: Oatmeal, Size: Queen, Color: Oatmeal
I did not open or use this sheet set because the color wasn’t suitable for the occasion I intended. I prefer to return items in unused condition so they can be resold as new, so I cannot comment on the exact fit. From a price point, it's value for money. From touching the fabric through the packaging, the material feels soft and of fair quality. There is no unpleasant smell, and the overall functionality seems fine based on its construction. My only disappointment is the oatmeal color—it looks somewhat dull and gives off an aged or slightly used appearance. I was hoping for a brighter, creamier tone. Aside from the color issue, the product appears to be well made and comfortable, which is why I’m giving it four stars.
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Reviewed in the United States on December 6, 2025
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Verified Purchase
Anonymous
Los Angeles, US
★★★★★ 5
Nice and soft
Size: Queen, Color: Chambray
Update: I’m very happy with this sheet set! I’m currently only using the fitted sheet as I don’t have a need for the top sheet or pillow cases right now. It hasn’t popped off the mattress at all like the previous cheep sheet I had. Original post: The sheet set arrived today. Haven’t actually tried it yet because I need to wash it first. From I can see, looks great. Once it’s washed and on my bed, and can figure out how to update my review I will do so accordingly. It’s soft like most people have said and the color is nice, though they didn’t have my favorite color purple in a shade I like so I got the ‘fancy blue’ (don’t remember the actual name of the color) because I desperately needed a new sheet of quality.
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Reviewed in the United States on March 1, 2026
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Verified Purchase
Donna A.
Carnegie, US
★★★★★ 5
Very comfy sheets, nice fabric
Size: Full, Color: Oatmeal
I wasn’t expecting such good quality forthis price. They’re very soft, but of fairly thick fabric. I’m sleeping great on them. The pockets are deep enough for an 8” foam mattress plus my 3” topper. Will be getting another set for the second bedroom.
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Reviewed in the United States on April 13, 2026
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H. Simon
Draper, US
★★★★★ 5
Great Sheets!
Size: Twin, Color: Oatmeal
Super soft, wash up beautifully, seem well made — very happy! It’s very hard to find 100% cotton t-shirt type sheets and these are really lovely.
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Reviewed in the United States on June 1, 2026
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Chris
Bozeman, US
★★★★★ 3
Weirdly textured
Size: King, Color: Dark Gray
I have bought and loved jersey sheets in the past, that have all been as soft as a well worn cotton t-shirt. These arent soft. They have the stretch of jersey, but not the soft smooth texture that they should have. Even after washing a few times these are one of my least favorite sheets I've ever bought on Amazon.
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Reviewed in the United States on May 30, 2026

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