SKU: 86566551744

Neprinol - Systemic Fibrinolytic Enzyme Therapy

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Description

Neprinol - Systemic Fibrinolytic Enzyme TherapySystemic Fibrinolytic Enzyme Therapy Support your long term vitality with Arthur Andrew Medical Neprinol, a clinical grade systemic enzyme formula designed to optimize cardiovascular function and joint comfort. Neprinol utilizes a high potency blend of proteolytic enzymes, including Nattokinase and Serrapeptase, to assist the body in maintaining healthy fibrin levels. Fibrin is a protein essential for recovery, but its overproduction as we age can

Systemic Fibrinolytic Enzyme Therapy

Support your long-term vitality with Arthur Andrew Medical Neprinol, a clinical-grade systemic enzyme formula designed to optimize cardiovascular function and joint comfort. 

Neprinol utilizes a high-potency blend of proteolytic enzymes, including Nattokinase and Serrapeptase, to assist the body in maintaining healthy fibrin levels. Fibrin is a protein essential for recovery, but its overproduction as we age can lead to fatigue, joint stiffness, and reduced circulatory efficiency. 

By promoting natural fibrinolysis (the breakdown of excess fibrin), Neprinol helps cleanse the blood of non-living protein debris, supporting healthy blood viscosity and arterial elasticity. 

This advanced blend also features CoQ10 and Magnesium to fuel cellular energy and support a steady heart rhythm. Experience a comprehensive approach to healthy aging that enhances nutrient delivery, boosts natural immunity, and promotes a balanced inflammatory response throughout the entire body.

  • Optimize Cardiovascular Circulation: Supports the heart and vascular system by maintaining fluid blood flow and healthy blood viscosity.
  • Maintain Healthy Fibrin Levels: Features premier fibrin-fighting enzymes to help the body manage excess protein buildup in the bloodstream and tissues.
  • Support Normal Blood Pressure: Helps maintain arterial health and elasticity to support blood pressure levels already within a normal range.
  • Enhance Joint Mobility and Comfort: Assists in reducing the protein-based debris that can lead to occasional joint stiffness and physical discomfort.
  • Promote a Balanced Inflammatory Response: Systemic enzymes work throughout the body to support natural recovery processes and internal harmony.
  • Boost Natural Immune Function: Cleanses the blood of cellular waste, allowing the immune system to focus on maintaining a resilient defense environment.
  • Support Cellular Energy and Heart Health: Includes CoQ10 to provide essential antioxidant protection and fuel for mitochondrial function.
  • Combat Age-Related Fatigue: Helps counteract the natural decline in enzyme production to sustain high energy levels and systemic performance.
  • Promote Healthy Tissue Repair: Supports the body's inherent ability to manage scar tissue formation and maintain structural integrity after physical exertion.
  • Clinical Strength and Bioavailable: Engineered to survive the digestive tract and reach the bloodstream for maximum systemic effectiveness.

Details

Benefits of Ingredients

  • Support Healthy Cardiovascular Circulation: A high-potency combination of Nattokinase and Serrapeptase assists the body in maintaining normal blood viscosity and clear vascular pathways by breaking down excess fibrin.
  • Promote Systemic Protein Cleansing: Protease, Bromelain, and Papain work together to dismantle non-living protein debris throughout the bloodstream, supporting the body’s natural recovery and detoxification processes.
  • Enhance Cellular Energy Production: CoQ10 acts as a vital antioxidant and metabolic cofactor, providing the necessary fuel for mitochondrial function and heart muscle vitality.
  • Optimize Nutrient Absorption and Metabolism: Lipase facilitates the efficient breakdown of dietary fats, while Protease ensures proteins are converted into bioavailable amino acids for tissue repair.
  • Support Healthy Inflammatory Responses: Plant-derived enzymes and Rutin help modulate the body’s internal recovery signals, promoting joint comfort and physical resilience after exertion.
  • Maintain Antioxidant Defense: Amla, a potent source of natural vitamin C, works with Rutin to protect cells and blood vessels from oxidative stress and free radical damage.
  • Encourage Muscle Relaxation and Nerve Function: Magnesium provides essential electrolyte support to help manage occasional muscle tension and support a steady, healthy heart rhythm.
  • Strengthen Vascular Integrity: Rutin and Amla provide bioflavonoids that support the structural strength and elasticity of capillaries and arterial walls.

The Science of Systemic Enzymes and Fibrinolysis

Systemic enzymes differ from digestive enzymes by entering the bloodstream to act as biological catalysts throughout the entire body. While digestive enzymes break down food in the stomach, systemic enzymes are absorbed to dismantle excess fibrin and protein based waste, a process vital for maintaining clear circulatory pathways and supporting natural repair mechanisms. 

Fibrin is a structural protein used in scar tissue and blood clotting, but age or stress can cause imbalances that increase blood viscosity. Nattokinase and other fibrinolytic enzymes trigger a process called fibrinolysis, which safely breaks down these protein structures to restore smooth circulation.

Clinical testing shows this microbial and plant based blend is more than 500% stronger in fibrinolytic activity than leading animal based formulations while remaining vegan friendly. Maintaining a healthy fibrin equilibrium prevents blood from becoming too thick or sticky, which otherwise increases friction against vessel walls and decreases oxygen delivery to tissues. A healthy body naturally secretes plasmin to remove unnecessary proteins and maintain normal thickness, but as natural production slows with age, supplementing with fibrinolytic enzymes supports this essential blood cleansing process.

Beyond circulatory health, these enzymes provide effective immune system support by helping to eliminate proteins created when antibodies deactivate antigens like pollen or bacteria. This enzymatic potency supports the natural repair process and limits inflammation from overexertion. 

Because enzymes are substrate specific, acting like a lock and key, they only react with certain harmful proteins without breaking down vital tissues. Taking these enzymes on an empty stomach allows them to enter the bloodstream fast to work systemically. 

While individual results vary, the most significant benefits for normalizing blood viscosity and supporting overall well-being typically occur within one to three months of consistent use.

Ingredients

Contains:
Nattokinase, Serrapeptase, Lipase, Bromelain, Papain, Protease, Amla, Rutin, CoQ10, Magnesium.

Other Ingredients:
Cellulose (Acid Armor) capsules are specialized, high-density plant-based veggie capsules (HPMC) designed to act as a natural, enteric-coated alternative to plastic-based (phthalate) coatings. They protect sensitive ingredients like enzymes from stomach acid and delay release by roughly 45 minutes, allowing them to pass into the intestines. 

  • Natural Protection: Unlike traditional enteric coatings that use synthetic plastics (phthalates), Acid Armor capsules use thick cellulose, making them healthier and often vegetarian/kosher friendly.
  • Delayed Release: They are engineered to delay the release of contents by an average of 45 minutes, ensuring ingredients pass through the acidic stomach (~30 minutes travel time) before opening, which is ideal for probiotics and enzymes.
  • High Stability: These capsules have low moisture content, making them suitable for sensitive ingredients that might otherwise degrade.
  • Secure Locking: They often feature a micro-threaded mechanism to prevent premature leakage of the contents.
  • Uses: Primarily used for supplements requiring protection from stomach acid.

Free From:
Dairy, gluten, soy allergens, artificial colors and preservatives.

  • Kosher (copy of certification available by request)
  • Vegetarian in accordance with the guidelines of the American Vegetarian Association.
  • Non-GMO (genetically modified organism) as defined by the National Organic Standards Board (copy of certification available by request)
  • GRAS (generally recognized as safe) by the FDA.

Instructions

Directions for Use

Take with 8 ounces of water, on an empty stomach (at least 1 hour before eating or 2 hours after).

Larger daily doses should be divided into 2 or 3 servings per day.

Maintenance: 2 to 3 capsules per day.

Increased Support: 4 to 6 capsules per day.

Therapeutic: 9 capsules per day

Neprinol can be used safely with other dietary supplements.

Store in cool, dry place with lid tightly closed.

Recommended Use

Optimize cardiovascular health, normal blood pressure and fibrin. Boosts immunity, joint mobility and comfort, tissue repair and balanced inflammatory response. Combats age related fatigue.

Contraindications

If you are taking blood thinners, please monitor your blood properties carefully with your doctor.

Do not take this product without the consent of your physician if you are currently taking blood-thinning medications, or if you are pregnant or nursing.

Ingredients that affect blood clotting and should NOT be taken with Nattokinase:

  • Ascorbate
  • Garlic Powder
  • Hawthorn
  • Vinegar
  • Black Sesame paste
  • Grape Seed Extract
  • Polyphenol from Apple

Keep out of reach of children.

Scientific References

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 86566551744

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mp77
Fort Morgan, US
★★★★★ 4
Large is a little big for Bostons
Color: Dogwood (Brown), Size: Large (Pack of 1)
Seems to be durable for 2 VERY agressive chewer Boston Terriers. Cricket and Alice are shockingly good at chewing - grateful they pick to do so with thier toys. Trial vs other name brand competitor. PetStages' is a little larger so harder to bite on fir small dogs, but seems to be equally durable. While PetStages proudly states it has real wood fiber and scent (whoch I thought would win)... they prefered the other. Both dogs love to chew on real sticks. But, when the bossy one indicated she was taking over the stick the other dog had, they exchanged, and kept chewing, over and over, back and forth. I mean to say, whatever the prefered stick was at first didnt seem to matter later. These super hard chew toys do make me nervous. One dog broke a tooth last summer on a different brand toy, a very expensive extraction bill, and poor pup's terrible discomfort... but the other did not and has amazing white teeth, all around.... so.
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Reviewed in the United States on September 26, 2025
M
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Michael F Doyle
Boise, US
★★★★★ 5
Great for teething puppies
Color: Dogwood (Brown), Size: Small (Pack of 1)
My pup absolutely loves this. Can keep him occupied for up to 45 min at a time. Pretty durable, too.
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Reviewed in the United States on May 8, 2026
J
Verified Purchase
Just my opinion
Birmingham, US
★★★★★ 5
The best chew ever for a strong chewer
Color: Dogwood (Brown), Size: Large (Pack of 1)
We have a 77lb goldendoodle who loves these. We’re lucky because he doesn’t chew on anything other than his toys, but when he starts on this…he really goes at it. It’s healthy, (not synthetic), doesn’t break apart, (no pieces to worry about him swallowing), it just perfect for him. The noise may get on your nerves but it’s a small price to pay to keep him from chewing on your furniture, shoes, or anything else a mischievous dog can find.
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Reviewed in the United States on May 30, 2026
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Kylie
Lowell, US
★★★★★ 3
Little pieces break off
Color: Dogwood (Brown), Size: Large (Pack of 1)
My dog is obsessed with this. It does last a long time even given her strong chewing capabilities. I wish it was a little bigger. The main reason I rated it so low is when my dog is chewing on this it breaks off a little plastic peice and sometimes it hits the back of her throat making her cough so you have to supervise with this.
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Reviewed in the United States on February 1, 2026
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Heidi 
Natrona Heights, US
★★★★★ 5
Great for aggressive chewers
Color: Dogwood (Brown), Size: Large (Pack of 1)
My dog is an aggressive chewer so they are great for her. I would love to have one a bit thinner so it could fit in a holder so it is easier for her to hold while eating. This keeps her busy and is long lasting. I have purchased these multiple times.
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Reviewed in the United States on April 5, 2026

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