SKU: 75445417064

Malignant : How Bad Policy and Bad Evidence Harm People with Cancer

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Malignant : How Bad Policy and Bad Evidence Harm People with CancerHow hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In

How hype, money, and bias can mislead the public into thinking that many worthless or unproven treatments are effective. Each week, people read about new and exciting cancer drugs. Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel-but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which* promote novel cancer therapies long before credible data are available to support such treatment; and* exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars. Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration. This is a book about how the actions of human beings-our policies, our standards of evidence, and our drug regulation-incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says, * more cancer clinical trials should measure outcomes that actually matter to people with cancer;* patients on those trials should look more like actual global citizens;* we need drug regulators to raise, not perpetually lower, the bar for approval; and* we need unbiased patient advocates and experts. This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer-and how we can avoid repeating the policy and practice mistakes of the past.

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SKU: 75445417064

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Port Orchard, US
★★★★★ 5
The best sandals ever
Size: 8, Color: Black/White, Size: 8, Color: Black/White
These are the most comfortable sandals for the summertime! Not only is the design totally 90's inspired but I also feel like I'm walking on a couple of bouncy clouds! You will not regret buying these!
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Reviewed in the United States on May 26, 2026
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Chelsea, US
★★★★★ 5
Very pleased with these!
Size: 9, Color: Egret/Lavender/Multi
I wasn't sure about these, but have had good luck with other HEYDUDE shoes. So I ordered these. True to size. I'm pleasantly surprised. Very comfortable and cute. They don't look like the usual HEYDUDE frumpy shoes. But yet they provide the same comfort as frumpy HEYDUDES. (Nothing against frumpy HEYDUDES. I own a pair and wear them for comfort.)
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Reviewed in the United States on April 4, 2026
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noah
Houston, US
★★★★★ 1
Runs large and too squishy of a sole
Size: 9, Color: Black/White
Why did you pick this product vs others?: I really wanted to love these, but the fit was off, and the sole is extremely squishy, which on a platform shoe was nearly a disaster.  I wear an 8.5/9 in all my shoes. I got a size 9, and they were far too big. I also have wide feet and the straps still had excess room between the strap and the tops of my feet.  I tried the shoes on, took a few steps, and the sole was so squishy it felt like I was falling. If I had a size 8, instead of 9, maybe that would not have happened.  I ended up returning, but wish the fit was better as these are super cute shoes 
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Reviewed in the United States on June 19, 2025
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Jose Correa
Houston, US
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Stunning Automatic Watch With TopTier Durability and Precision
Color: Grey
“I got this Tissot PRX for my cousin’s birthday and bro fell in LOVE instantly. This thing keeps time like a beast, never slows down, never lags. Automatic movement, so no batteries, no drama. Durability? Stupid good. You can hit it, bump it, live life rough, it still looks box fresh. Size wise it was almost perfect. I just had to remove two links, nothing big. It’s light, functional, comfortable, doesn’t weigh you down, doesn’t get in the way but more importantly I can say this watch is in everyone’s eyesight when we wear it. Cause of course I had to get another one! Basically. I gave him a very nice piece as a gift, and now he’s walking around like he owns Switzerland.
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Reviewed in the United States on December 11, 2025
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Cienfuegos
San Leandro, US
★★★★★ 5
Great watch!!!!
Color: Grey
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