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Description
K9 Advantix II Flea, Tick & Mosquito Treatment & Prevention for Medium DogsK9 Advantix II Medium Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult
K9 Advantix II Medium Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Medium Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 11-20 lbs. to use K9 Advantix II Medium Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Medium Dog is a trademark of Elanco or its affiliates.
Key Features
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K9 Advantix II Medium Dog 30-day treatment & prevention protects dogs 11-20 lbs. from fleas, ticks, mosquitoes, biting flies and lice
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Kills fleas within 12 hours of application
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Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
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Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
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No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Medium
Pet Lifestage
- 7 weeks and older
Pet Weight
11-20 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.3 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 4
Provides cooling to tired eyes
These patches feel really good under your eyes. They are cooling, reduces puffiness, reduces discoloring and bags under the eyes. The only issue I have is not staying under the eye very well. Other than that they moisturize quite well and they are effective. The scent is very subtle so not to irritate your eyes. I use this line of products so I would definitely recommend
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Great for crows feet
I thought this was a cream it is actually patches. They adhere well and are great while sleeping. I noticed a reduction and wrinkles around my eyes after the first night. There was a generous supply of product on the patches and are worth the money.
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Reviewed in the United States on May 30, 2026
★★★★★ 5
One of My Favorite Multi-Use Patches — Great for Under Eyes and Smile Lines
At 52, post-menopausal, with dry, mature skin, I’m always looking for products that help with the areas that tend to show age first—especially the under-eyes and around the mouth. Those areas can lose firmness, show fine lines, and look more tired faster than the rest of the face. These patches have become one of my favorite targeted treatments.
First, I love how easy they are to use. The patches are well saturated, comfortable on the skin, and stay in place nicely once applied. That alone matters because so many eye patches slide around and become more annoying than helpful. These feel secure and simple to wear while getting ready or relaxing.
What I noticed most under the eyes was that the area looked more hydrated, smoother, and fresher after use. Puffiness looked reduced, fine dehydration lines were softened, and the skin had a more rested appearance. No, they are not going to permanently erase aging overnight, but they absolutely help the area look better.
I also appreciate that they do more than just add temporary moisture. With regular use, the under-eye area looks better maintained and less tired overall.
Another reason I love these is that I also use them on my smile lines / nasolabial area. That has been a great bonus. The curved shape works surprisingly well for placing around the mouth, and the extra hydration helps soften lines and improve the look of that area too.
That multi-use flexibility makes the product much more valuable to me than standard eye patches.
The formula feels cooling and refreshing, and I like using them before makeup or before going out when I want my skin to look a little smoother and more awake.
I also appreciate the ingredient direction. Dr. Melaxin tends to focus on firmness, support, and mature-skin concerns rather than trendy fluff, and that’s one reason I keep coming back to the brand.
Who I think these are great for: mature skin, dry under-eyes, puffiness, fine lines, smile lines, travel days, special-event prep, or anyone wanting targeted treatment patches.
Who may want to skip them: people expecting permanent wrinkle removal, anyone who dislikes patch-style skincare, or those wanting the cheapest basic eye patch option.
Value-wise, I think these are excellent because you can use them in more than one area and actually see a visible cosmetic benefit.
I’ve used many patches over the years, and these are among the better ones.
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Reviewed in the United States on April 19, 2026
★★★★★ 5
great product
my favorite i use every single night and i don’t wake up with puffy eyes anymore
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Reviewed in the United States on May 21, 2026
★★★★★ 5
Worth it!!
These are my favorite eye patches because they stay put, blend well so you don’t look freaky if you’re wearing them during the day etc. and they work! They’re my go to when my under eyes need some extra help, which in my mid 50’s is almost all the time!! Worth the money!!
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Reviewed in the United States on May 29, 2026
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